In this version, the destruction of the Earth Kingdom and Moon Kingdom was caused by her, in her sorrow over Prince Endymion's death. According to Minako, Serenity used to be a kind and peaceful girl, much like Usagi in her present incarnation, but that changed after the destruction of the Moon Kingdom and the Earth Kingdom, making her cold and ruthless and always believe that her and Endymion's destiny was only to separate, even if they were born on the same planet, Earth.

After the Princess within Usagi was awakened, she began to slowly take over, and took control of Usagi's body when she was suffering from sadness, loneliness, or anger. When Mamoru was threatened, Usagi would transform into Princess Sailor Moon against her will. It was clear that Serenity had full control Princess Sailor Moon, leading to an internal conflict with Usagi for the remainder of the series.

As Serenity selfishly refused to see the consequences of her actions that it would have on Earth, claiming that she has no qualms in destroying the Earth if Endymion was ever taken away from her. Usagi underwent endurance training to keep both her and the Silver Crystal in line. For a while, she was successful in keeping both the crystal and Serenity at bay. However when Usagi was forced to kill off a possessed Mamoru, Princess Serenity overcame her resistance, transformed into Princess Sailor Moon and successfully destroyed the planet. Eventually, she realized the full extent of the consequences it brought her when she ignored Usagi's warning by destroying the planet and grieved the loss of life on Earth. Upon seeing Endymion who encouraged her to use the Silver Crystal again to reverse the destruction, Serenity did out of love and finally made peace with Usagi. The Senshi lost their power to transfrom as the Silver Crystal was destroyed but in the Special Act, Queen Serenity sent a sword to Earth that would give the Senshi their powers back for one day.