I wanted to start a thread for us to share our shows we love that got the boot on TV or had a nice closure after many seasons.

Flash Forward
The Lying Game
Huge
Make It or Break It
The Secret Life of the American Teenager
Twisted
Private Practice
Crisis
The Cosby Show
Thats So Raven
In Living Color

Omg, Make It or Break It! I loved that show so much. Like it actually hurt that you didn't get to see the go to the Olympics.
And Twisted. 

Some others for me were Firefly, Kyle XY, Fresh Prince of Bell Air, Miranda (which sadly just finished), Drop Dead Diva, Cult, Star-Crossed (mostly for Matt Latner)... and far more than aren't coming to mind right now.

lets see theirs several shows I've watched and loved over the years 

Birds of prey
Buffy the Vampire slayer
Charmed
Angel
Boy meets world
Saved by the bell
Moonlight
Louis and Clark: the new adventures of superman (i've always been a big superman fan)
Hercules the legendary journeys
Xena: Warrior Princess (Xena was my hero growing up)
Sabrina the teenage witch

I'm sure theirs several more that I've forgotten to list

The Nanny
That's 70's show
Malcom in the Middle
All That
Icarly
DRAKE AND JOSH MY BOYS
The crocodile hunter (Though it...wasn't cancelled.  )

Omg, super yes to Buffy, which I have started rewatching. Such a great (but campy at times) show!
And The Nanny! Oh man, I grew up watching that.

the Nanny- I loved that show so much.

Most recently...  BREAKING BAD.

oh just remembered one I forgot and that would be Mighty Morphin Power rangers *has rewatched the series 20 million times but still misses it*

Friends
King of the hill

M*A*S*H

This is a show my parents shared long before I was around, but we watched it when we could as a family. They always got so excited about certain episodes and the show was always on point and well done.

Ah, my old fandom heartbreaks.

Charmed
ALIAS (what even is that ending though)
Legend of the Seeker (really got screwed over)
Nikita
Dollhouse
Pushing Daisies
Tru Calling

There are also others but mostly stuff I was happy were over because they'd run for a long time/devolved so badly it needed to end.

-Friends
-M*A*S*H
-The Nanny (I had a small "obsessed with Fran Drescher" phase as a teenager... but the show itself was awesome)
-The George Lopez Show
-Drake & Josh (This comparison vid is the only high quality of the opening I could find...)

Oh yes I loved mash and the nanny. I almost gotta meet Jamie farr once *whistels innocenty* 

Hmm theres also Young Riders it was a show my mother watched when she was a teenager and she talked me into sitting down and watching it with her when she found it on dvd fell absoltly in love with the series.

The Brady Bunch
Laverne and Shirley
Family Ties
Who's the boss
Alf
home improvement
Lizzie McGuire

I will admit most of these shows I've only seen as repeates but I loved them all.

Charmed
Xena 
Hercules
Firefly 
Unsolved Mysterious

Lost. Though I haven't finished it yet.
Also, Phineas and Ferb just ended, and as far as I'm concerned, my childhood is over.

How did I miss this topic?

Ocean Girl
Spellbinder
Carmen Sandiego(PBS style)
Kidsongs(never really had a series-but still awesome)
Ghostwriter-this one was devolving so badly it had to end though.
Saved by the Bell-actually my sister enjoyed this and I would watch it with her
Power Rangers-I watched all the way to space and then stopped because of when it aired
And I'm sure there's others that I can't think of at the moment.

- Thats so Raven
- Carmen Sanediego (Most of the a cappella group on there but i liked the show too)
- Power Rangers (First couple original seasons)
- Wishbone (PBS)
- GhostWriter
- Buffy The Vampire Slayer
- Bones (Fox show but not sure if last season was well..the last one)
- Hey Dude! (Old NICK show set in old west)
(Probably a bunch of others and a whole lot of animated ones too)

Thanks to Youtube, I can check on some reruns of popular paranormal TV series like Sightings (1990s on FOX) and In Search of... (1970s hosted by Leonard Nimoy). Artemis, King of the Hill is still on air on Adult Swim in evenings.

Not including my fave (western) animated shows or my fave late-night talk shows (there was only one of the former but several of the latter), I can only come up with a couple now.

Cheers
and the virtually-unheard-of British series
Travel Sick

To prove how unheard-of Travel Sick is, even the 'has information on everything' Wikipedia only has two short paragraphs in its stub article on this very-underrated (IMHO) TV series

Wikipedia wrote:

Travel Sick was a British hybrid comedy-travel television series that originally aired on Bravo from 2001 to 2002. It placed UK writer Grub Smith in a different region of the world in each episode. In each destination, he was asked to complete five undesirable challenges posed by the show's producers. If he failed a challenge, he was forced to perform something unpleasant called a "forfeit". The more he failed, the worse the "forfeit" at the end of the show became.

The series has also aired on Comedy Central in the United States.

I must add that I believe Travel Sick was infotainment at its best.  It was informative, giving real facts about the culture and other things of the geographic area where he was (usually such facts related to the Challenge he was about to undergo).  And it was very entertaining, having many things to laugh out loud about (even by my semi-picky comedy tastes) in each episode.  It really is a shame only two seasons of this were ever made.